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NeuroImaging & Electrophysiology Facility (NIEF)

//NeuroImaging & Electrophysiology Facility (NIEF)
NeuroImaging & Electrophysiology Facility (NIEF) 2017-08-10T13:38:15+00:00

The NeuroImaging and Electrophysiology Facility (NIEF) provides state of the art instrumentation and support to the COBRE Puerto Rico Center for Neuroplasticity investigators and the biomedical research community in Puerto Rico and Latin America. The COBRE Puerto Rico Center for Neuroplasticity consolidates the NeuroImaging Facility at the Institute of Neurobiology and the Confocal Imaging Facility at UPR (CIF-UPR) bringing the latest technology in imaging and electrophysiology to the Molecular Sciences Research Center.

For the past 20 years, the UPR has strengthened research quality in an effort to facilitate a transition towards competitive scientific research projects. The NIEF expanded these efforts by establishing a facility equipped with modern imaging and electrophysiology instrumentation. This desire is driven by the increasing importance that imaging and electrophysiology data has gained in the field of neuroplasticity. A formal partnership between UPR and the leading microscopy equipment provider Nikon was established forming the Nikon Center of Excellence. The NIEF provides users the capacity to study neuroplasticity by taking advantage of state of the art instrumentation and the integration of imaging and electrophysiological applications.

Of key importance is the facility’s capacity to detect fluorescence emissions from diverse biological preparations through confocal microscopy and two-photon microscopy while making electrophysiological measurements simultaneously. For instance, recent research provides examples of the power of coupling patch clamp electrophysiology techniques with calcium imaging. The facility provides training opportunities for students, postdoctoral fellows, and faculty in imaging techniques for the study of biological preparations. The NIEF is a completely self-sustained neuroimaging and electrophysiology research facility and a role model for Puerto Rico and the Caribbean.

The NIEF was established and is supported by NIH grant 1P20 GM103642 01A1 and by University of Puerto Rico institutional funds.

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